Zhang C
Dept. of Epidemiology, Beijing Medical University.
Zhonghua Liu Xing Bing Xue Za Zhi. 1992 Dec;13(6):321-4.
A case-control study was conducted among 250 persons suffering from cancer of the colon and rectum (CRC) in the urban area of Beijing from Jan 1, 1988-June 30, 1989 to explore the risk factors for CRC. 500 neighbour residents were matched as control. The chi-square test and conditional logistic Regression analysis show that high consumption of meat, oil, low occupational physical activity and psychological stress were risk factors of CRC. A trend of increased odds ratio (OR) of CRC with high meat intake and a trend of decreased OR with increased occupational physical activity were found. The high consumption of vegetables and the habit of eating uncooked fresh vegetables showed a protective effect on CRC. The results of the study support the CRC etiological hypotheses of "fat-bile acid action" and "deficiency of dietary fibres".
1988年1月1日至1989年6月30日期间,在北京城区对250例结肠直肠癌(CRC)患者进行了一项病例对照研究,以探讨CRC的危险因素。选取500名邻居居民作为对照。卡方检验和条件逻辑回归分析表明,肉类、油脂的高摄入量、低职业体力活动和心理压力是CRC的危险因素。发现随着肉类摄入量的增加,CRC的比值比(OR)有上升趋势,而随着职业体力活动的增加,OR有下降趋势。蔬菜的高摄入量以及食用未烹饪新鲜蔬菜的习惯对CRC有保护作用。该研究结果支持“脂肪-胆汁酸作用”和“膳食纤维缺乏”的CRC病因假说。