[布基纳法索恶性疟原虫对氯喹的体内化学敏感性：1988 - 1990年抗药性的发展]
[In vivo chemosensitivity of Plasmodium falciparum to chloroquine in Burkina Faso: development of resistance 1988-1990].
作者信息
Pietra V, Lamizana L, del Nero L, Rotigliano G
机构信息
Centre de Lutte contre le Paludisme, Ouagadougou, Burkina Faso.
出版信息
Parassitologia. 1992 Dec;34(1-3):131-4.
PMID:1339966
Abstract
A study of Plasmodium falciparum sensitivity to chloroquine was carried out in 1988 and 1990 in 5 localities, representatives of different climatic areas of Burkina Faso. The 7-day in vivo standard test performed in 1988 showed a total clearance failure of 25%. No significant difference with 1990 data was found, except for an increase of the resistance in the area of Fada N'Gourma, close to the border with Benin, Niger and Togo.
摘要
1988年和1990年在布基纳法索不同气候区的5个代表地点开展了一项关于恶性疟原虫对氯喹敏感性的研究。1988年进行的为期7天的体内标准试验显示总清除失败率为25%。除了与贝宁、尼日尔和多哥接壤的法达恩古尔马地区耐药性有所增加外，未发现与1990年数据有显著差异。
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