Touquet S, Martin P, Poisson D M, Bercault N, Fleury C, Gueveler C
Service de réanimation polyvalente, Centre Hospitalier Régional d'Orléans.
Agressologie. 1992;33 Spec No 3:140-2.
Polyurethane (PU) and polyethylene (PE) central venous catheters were compared for their respective responsabilities in catheter related sepsis (CRS). From may 1988 to may 1989, 300 central venous catheters were inserted. Insertion sites were freely chosen by physicians. The polymer type was randomized. Catheters were removed after 10 days in place. Microbial loads were assessed on insertion sites, catheter hubs and tips, and blood drawn through the catheters lumen. One hundred eighty three catheters were available for complete evaluation (101 PE, 82 PE). Eleven were responsible for CRS, 4 were colonized (BB3 according to Brun-Buisson's classification), 19 were contaminated (BB2), and 149 were sterile (BB1). When comparing the "infected" group (CRS+BB3) and the "noninfected" (BB2 + BB1), no difference appeared between the tested polymers. CRS were significantly associated with insertion into the internal jugular vein. It seems useless to exclude from clinical practice any of the biomaterials tested.
对聚氨酯(PU)和聚乙烯(PE)中心静脉导管在导管相关败血症(CRS)中的各自作用进行了比较。1988年5月至1989年5月,共插入300根中心静脉导管。插入部位由医生自由选择。聚合物类型随机分配。导管在位10天后拔除。对插入部位、导管接头和尖端以及通过导管腔抽取的血液进行微生物负荷评估。183根导管可供完整评估(101根PE导管,82根PU导管)。11根导致CRS,4根被定植(根据Brun-Buisson分类为BB3),19根被污染(BB2),149根无菌(BB1)。比较“感染”组(CRS + BB3)和“未感染”组(BB2 + BB1)时,所测试的聚合物之间未出现差异。CRS与插入颈内静脉显著相关。从临床实践中排除任何一种测试的生物材料似乎并无必要。