Giełdanowski J, Dutkiewicz T, Samochowiec L, Wójcicki J
Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.
Arch Immunol Ther Exp (Warsz). 1992;40(5-6):291-5.
The effect of Padma 28 on selected parameters of humoral and cellular immune reactions in rabbits subjected to experimental atherosclerosis was studied. The drug significantly reduced the size of atherosclerotic plaques in the aorta and restored to a varying extent the immune functions studied. The possible mechanism by which Padma 28 may exert its anti-atherosclerotic action is discussed in the scope of the immunological theory of atherosclerosis.
研究了Padma 28对实验性动脉粥样硬化家兔体液和细胞免疫反应选定参数的影响。该药物显著减小了主动脉粥样硬化斑块的大小，并不同程度地恢复了所研究的免疫功能。在动脉粥样硬化的免疫学理论范围内讨论了Padma 28可能发挥其抗动脉粥样硬化作用的潜在机制。
