Arellano J, Granados J, Frenk P, López-Osuna M, Santos I, Kretschmer R R
Departamento de Immunología y Reumatología INN Dr. Salvador Zubirán SS, UNAM, DF.
Arch Med Res. 1992;23(2):269-70.
Mexican mestizo pediatric patients with ALA revealed a significantly increased frequency of HLA-DR3 alone, or in its haplotype form HLA-A2, DR3, which confirms our previous observation in adult patients with ALA in the same ethnic group. However, the relative increase in these HLA specificities in pediatric ALA patients when compared to adult patients was not statistically significant, and calls for an enlargement of the population studied.
患有急性淋巴细胞白血病(ALA)的墨西哥混血儿科患者单独出现HLA - DR3或其单倍型形式HLA - A2、DR3的频率显著增加,这证实了我们之前在同一族群成年ALA患者中的观察结果。然而,与成年患者相比,儿科ALA患者中这些HLA特异性的相对增加在统计学上并不显著,因此需要扩大研究人群。