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[不同病因脑膜炎患儿及青少年中移植 HLA 抗原的分布]

[Distribution of transplantation HLA antigens in children and adolescents with meningitis of various etiology].

作者信息

Feĭzullaeva N A

出版信息

Probl Tuberk. 1999(2):43-4.

Abstract

An interaction between HLA antigens and predisposition to meningitis of specific and nonspecific etiology was studied in children and adolescents from an Azerbaijan population. The distribution of HLA antigens was found to be heterogeneous in the patients with meningitis of various etiology. Tuberculous meningitis was characterized by a significant rise in the detection rate of HLA-DR3 antigen, by a considerable frequency of B14 and DR2 antigens; patients with purulent meningitis much more significantly showed HLA-B12 antigen; in terms of locus A, there was an increase in the detection rates of HLA-A19 antigen in serous meningitis.

摘要

对阿塞拜疆人群中的儿童和青少年进行了研究,以探讨HLA抗原与特定和非特定病因脑膜炎易感性之间的相互作用。结果发现,各种病因脑膜炎患者中HLA抗原的分布存在异质性。结核性脑膜炎的特征是HLA-DR3抗原检出率显著升高,B14和DR2抗原出现频率较高;化脓性脑膜炎患者中HLA-B12抗原的表现更为显著;在A位点方面,浆液性脑膜炎中HLA-A19抗原的检出率有所增加。

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