Leprat F, Austyn C, Commenges-Ducos M, Commenges D, Cochet C, Basse-Catalinat B, Ducassou D, Latapie J L
Service d'endocrinologie, Hôpital Haut Lévèque, Pessac.
Ann Endocrinol (Paris). 1992;53(5-6):224-9.
A decreased bone mineral density is a well known complication of thyrotoxicosis. If bone is also adversely affected by a subclinical hyperthyroidism is still debated. Such a situation is deliberately induced for treatment of thyroid differentiated carcinoma. We compared bone mineral measurements in case of thyroid carcinoma exposed to prolonged suppressive hormonal treatment (288 patient year, LT3 in 87%) and in age and weight matched controls. We did not find any difference in both sexes between the two populations in term of fracture rate and vertebral mineral density measured by dual photon absorptiometry, nor any influence of gonadal status in women.
