Chabert-Orsini V, Conte-Devolx B, Thiers-Bautrant D, Atlan-Gepner C, Denizot A, Audiffret J, Henry J F, Codaccioni J L
Service d'Endocrinologie et maladies métaboliques, Hôpital de la Conception, Marseille.
Presse Med. 1990 Nov 10;19(37):1709-11.
Thyrotoxicosis may be held responsible for osteoporosis. The question is whether a very slight subclinical hyperthyroidism, as is desirable in the post-operative treatment of differentiated thyroid carcinoma, can in the long run be detrimental to bone tissue. In a series of 37 patients, aged 50.9 +/- 11.1 years, presenting with the features of subclinical hyperthyroidism of 8.0 +/- 4.8 years duration, the authors have been unable to find any change in paraclinical parameters of bone and calcium-phosphate metabolism. Thirty-six of these 37 patients showed no abnormal decrease of vertebral bone density measured by dual photon absorptiometry.