Gundidza M, Sorg B, Hecker E
Department of Pharmacy University of Zimbabwe, Mount Pleasant, Harare.
Cent Afr J Med. 1992 Dec;38(12):444-7.
From the fresh latex of Euphorbia cooperi N E Br was isolated by partition and chromatographic methods, a diterpene ester 12-deoxyphorbol-16-isobutyrate-13-tigliate. The phorbol ester exhibited highly irritant activity on the mouse ear. Since skin irritancy is an indication of possible tumour promotion, the use of this plant as a medicine should be discouraged.
通过分配和色谱法从库珀大戟的新鲜乳胶中分离出一种二萜酯12-脱氧佛波醇-16-异丁酸酯-13-巴豆酸酯。该佛波醇酯对小鼠耳部表现出高度刺激性活性。由于皮肤刺激性是可能促进肿瘤的一个指标，因此不鼓励将这种植物用作药物。
