Gundidza M, Kufa A
Department of Pharmacy, Faculty of Medicine, University of Zimbabwe, Mount Pleasant, Harare.
Cent Afr J Med. 1993 Mar;39(3):56-60.
A crude ethylacetate extract was isolated from Euphorbia bougheii by a combination of solvent-solvent and chromatographic methods. The extract exhibited significant skin irritant activity on the mouse ear as well as a tumour promoting activity on the mouse back skin. This indicates that the use of this plant as a medicine must be discouraged since the latex extract causes cancer.
通过溶剂萃取和色谱法相结合的方法，从布氏大戟中分离出粗制乙酸乙酯提取物。该提取物对小鼠耳部表现出显著的皮肤刺激活性，对小鼠背部皮肤也有促肿瘤活性。这表明，由于该乳胶提取物会致癌，必须不鼓励将这种植物用作药物。
