The effects of immobilization stress on electrodermal activity and brain catecholamine levels in rats.

The effects of immobilization stress on electrodermal activity (EDA); skin conductance response magnitude and rate, skin conductance level and habituation number, and brain catecholamine levels; norepinephrine (NE) and dopamine (DA) were investigated in rats. Electrodermal activity was recorded using constant current method. Brain catecholamine levels were determined by a spectrophotophlorometric method. Electrodermal activity parameters (except skin conductance level) increased during immobilization. It was observed that, during immobilization stress, the alteration of norepinephrine and dopamine levels in rat brain was related to cerebral region and the duration of immobilization stress. It was concluded that these electrodermal activity alterations can be attributed to the changes in central norepinephrine metabolism induced by immobilization.