Laky D, Rădulescu D
Victor Babeş Institute, Bucharest, Romania.
Rom J Morphol Embryol. 1992 Jul-Dec;38(3-4):155-7.
Intestinal localization of rhabdomyosarcoma is exceptional, this case is the first to be published in the world literature. A 35-year-old patient with abdominal pain, fever, was found to have an infiltrative white-grey tumour, involving 20 cm the jejunoileal wall and also the surrounding mesenterium up to the origin of upper mesenterical vessels and lymph nodes. Histologic examination showed an alveolar type of rhabdomyosarcoma intricated with solid undifferentiated tumoral cells. The presence of multinucleated giant cells and the positivity of protein S 100 reaction was important for differential diagnosis, given the alveolar soft part sarcoma, malignant mesothelioma, malignant melanoma or papillary carcinoma.
横纹肌肉瘤发生于肠道极为罕见，该病例是世界文献中首次发表的此类病例。一名35岁腹痛、发热患者，被发现有一个浸润性灰白色肿瘤，累及空肠回肠壁20厘米，还包括周围肠系膜直至肠系膜上血管起始处及淋巴结。组织学检查显示为肺泡型横纹肌肉瘤，夹杂实性未分化肿瘤细胞。鉴于肺泡软组织肉瘤、恶性间皮瘤、恶性黑色素瘤或乳头状癌，多核巨细胞的存在及蛋白S 100反应阳性对鉴别诊断很重要。
