Handrock M, Baumgärtel A
Laryngol Rhinol Otol (Stuttg). 1976 Aug;55(8):644-53.
In 94 patients with allergic and non-allergic rhinopathy, we performed quantitative IgE-determinations in the serum as well as in the nasal secretion. 34 patients had a vasomotor rhinitis, 40 patients a pollinosis and 20 a perennial allergic rhinitis. Statistically, the IgE-values were in pollinosis and in perennial alllergic rhinitis-in the serum as well as in the nasal secretion-significantly higher than in vasomotor rhinitis. Due to the great range of variation of the values in all groups of patients examined, an assignment ot a certain group of diseases was not possible individually. As in some patients the secretion concentrations were higher than the corresponding serum values, we presume that IgE is produced-at least to some extent-also in the mucosa.