Kneissel H
Med Klin. 1976 Sep 10;71(37):1506-7.
During an operation for lumbar disk herniation, 160 patients were injected - intrathecally and peridurally, against the affected nerve root - one ampoule of Volon A40. The postoperative course was compared to that stated in 160 patients who had been operated in the same way without this medication. The irritation of the spinal root effected by the disk prolapse and the manipulation during the operation was immediately influenced in a favourable manner by Volon A40. The patients had no more complaints from the first postoperative day on. Mobilization of the patient could be started about three to four days earlier. During recurrency operations, the root did not show any adhesions. Prevention of postoperative cicatrization around the root appears to be an essential condition for a permanent state without complaints. The percutaneous intrathecal and peridural application of Volon A40 has proved to be efficacious in cases of lumbar root irritation, which can neither be treated surgically nor be influenced by a physical therapy.
在腰椎间盘突出症手术过程中，160例患者在鞘内和硬膜外针对患侧神经根注射了一支沃隆A40。将这些患者的术后病程与160例接受相同手术但未使用此药物的患者的术后病程进行了比较。沃隆A40对由椎间盘突出和手术操作引起的脊神经根刺激产生了立即且有利的影响。患者从术后第一天起就不再有不适。患者的活动可以提前大约三到四天开始。在再次手术时，神经根未显示任何粘连。预防神经根周围的术后瘢痕形成似乎是实现无不适的永久状态的必要条件。事实证明，对于既无法通过手术治疗也无法通过物理治疗改善的腰椎神经根刺激病例，经皮鞘内和硬膜外应用沃隆A40是有效的。
