García-Ramos Alonso E, Fernández-Caldas E, Seleznick M J, Lockey R F
Consejería de Sanidad y Servicios Sociales, Gobierno Autónomo de Canarias, Spain.
J Investig Allergol Clin Immunol. 1992 Jan-Feb;2(1):19-26.
The prevalence of skin test reactivity to 22 aeroallergens and of allergic respiratory diseases was determined in 501 high school students on the island of Tenerife, Spain. Two hundred seventy-seven students (55.2%) had at least one positive prick skin test (wheal > or = 2 mm). Two hundred sixteen students (43.1%) had symptoms of upper or lower respiratory tract allergies [24 (4.7%) had asthma with or without rhinitis and 192 (38.3%) seasonal or perennial rhinitis alone]. Two hundred eighty-five students (56.8%) were asymptomatic. One hundred per cent of the students with asthma, 87.5% of the students with rhinitis and 27.7% of the asymptomatic students had at least one positive skin test. The prevalence of positive skin tests was significantly higher in symptomatic than in asymptomatic students (p = 0.0001). One hundred seventy students (33.9%) had a family history of respiratory allergic diseases. The prevalence of positive skin tests among these students was significantly higher than in students without such history (p = 0.0001). Thus, there is a high prevalence of allergic respiratory diseases and skin test reactivity to aeroallergens among high school students in Tenerife. Significant correlations were found between family history, positive skin tests and respiratory allergic symptoms.
在西班牙特内里费岛的501名高中生中,测定了对22种气传变应原的皮肤试验反应性及过敏性呼吸道疾病的患病率。277名学生(55.2%)至少有一项皮肤点刺试验呈阳性(风团≥2毫米)。216名学生(43.1%)有上呼吸道或下呼吸道过敏症状[24名(4.7%)患有哮喘伴或不伴鼻炎,192名(38.3%)仅患有季节性或常年性鼻炎]。285名学生(56.8%)无症状。100%的哮喘学生、87.5%的鼻炎学生和27.7%的无症状学生至少有一项皮肤试验呈阳性。有症状学生的皮肤试验阳性患病率显著高于无症状学生(p = 0.0001)。170名学生(33.9%)有呼吸道过敏性疾病家族史。这些学生的皮肤试验阳性患病率显著高于无此类家族史的学生(p = 0.0001)。因此,特内里费岛的高中生中过敏性呼吸道疾病和气传变应原皮肤试验反应性的患病率很高。家族史、皮肤试验阳性和呼吸道过敏症状之间存在显著相关性。