Chong Neto Herberto José, Rosário Nelson Augusto, Westphal Gabriele Cardoso, Riedi Carlos Antônio, dos Santos Hevertton Luiz Bozzo Silva
Pediatric Allergy Division, Federal University of Paraná Curitiba, Paraná, Brazil.
Iran J Allergy Asthma Immunol. 2010 Mar;9(1):21-5.
The aim of this study was to assess the frequency of rhinitis in asthmatic infants. A cross-sectional study was conducted using clinical data obtained from a standardized allergy work-up form that includes specific questions on common allergic diseases. Asthmatic patients were seen at the first visit to the Pediatric Allergy Unit, from January 2001 to January 2006, were selected for analysis. Diagnosis of allergic rhinitis was based on the presence of two or more nasal symptoms (sneezing, itching, congestion and rhinorrhea). Allergic sensitization was assessed by skin prick test for Dermatophagoides pteronyssinus, Blomia tropicalis, Blattella germanica, Lolium perenne, dog and cat danders. Four hundred and ninety-three infants (under 2 years of age) were selected from a total of 1543 asthmatics aged 0-14 years, 58% males. Physician diagnosis of rhinitis in infants was registered in 367 (74%) and 131 (36%) had positive skin prick test to at least one allergen. Infants were more frequently sensitized to Dermatophagoides pteronyssinus (43%) and Blomia tropicalis (27%). Among asthmatic children > or =2 years old, 890 (84%) also had rhinitis, 773 (87%) were atopic. Among those children with rhinitis, one hundred and eighty six were fully skin prick tested with a standard panel of common aeroallergens. There was no difference between sensitization in asthmatic infants and older asthmatic children with allergic rhinitis. Thus the frequency of rhinitis in asthmatic infants as well as atopic sensitization were similar to older children.
本研究的目的是评估哮喘婴幼儿鼻炎的发病频率。采用从标准化过敏检查表格中获取的临床数据进行了一项横断面研究，该表格包含有关常见过敏性疾病的特定问题。选取2001年1月至2006年1月首次到儿科过敏科就诊的哮喘患者进行分析。变应性鼻炎的诊断基于两种或更多种鼻部症状（打喷嚏、瘙痒、鼻塞和流涕）的存在。通过对尘螨、热带无爪螨、德国小蠊、黑麦草、狗和猫皮屑进行皮肤点刺试验评估变应性致敏情况。从1543名0至14岁的哮喘患者中选取了493名（2岁以下）婴幼儿，其中男性占58%。医师诊断有鼻炎的婴幼儿为367名（74%），131名（36%）对至少一种变应原皮肤点刺试验呈阳性。婴幼儿对尘螨（43%）和热带无爪螨（27%）的致敏更为常见。在≥2岁的哮喘儿童中，890名（84%）也患有鼻炎，773名（87%）为特应性。在那些患有鼻炎的儿童中，186名用一组标准的常见气传变应原进行了全面的皮肤点刺试验。哮喘婴幼儿与患有变应性鼻炎的大龄哮喘儿童之间的致敏情况没有差异。因此，哮喘婴幼儿鼻炎的发病频率以及特应性致敏情况与大龄儿童相似。
