爪蟾可克隆品系LG7中免疫球蛋白基因座纯合的Cμ和VH1家族序列，爪蟾为非洲爪蟾属。 （备注：原文对于Xenopus未详细解释，这里补充完整，仅供参考）
Sequences of C mu and the VH1 family in LG7, a clonable strain of Xenopus, homozygous for the immunoglobulin loci.
作者信息
Wilson M, Marcuz A, Courtet M, Du Pasquier L
机构信息
Basel Institute for Immunology, Switzerland.
出版信息
Dev Immunol. 1992;3(1):13-24. doi: 10.1155/1992/74187.
Twenty-eight heavy-chain variable (VH1) region genes and the immunoglobulin (IgM) heavy-chain constant region of an isogenic Xenopus hybrid, X. laevis/X. gilli, LG7, have been sequenced. The LG7 clone represents the first Xenopus hybrid that is homozygous for the IgH locus. The VH1 family was specifically investigated because VH1 genes are used by the antibodies produced during the Xenopus antidinitrophenol (DNP) response, These VH1 germ-line sequences establish a so-called "dictionary" that is available for studying somatic hypermutational mechanisms in immunized frogs.
对同基因非洲爪蟾杂交种X. laevis/X. gilli的28个重链可变（VH1）区基因以及免疫球蛋白（IgM）重链恒定区进行了测序，该杂交种为LG7。LG7克隆代表了首个在免疫球蛋白重链（IgH）基因座上纯合的非洲爪蟾杂交种。之所以专门研究VH1家族，是因为非洲爪蟾抗二硝基苯酚（DNP）反应产生的抗体使用了VH1基因。这些VH1种系序列建立了一个所谓的“词典”，可用于研究免疫青蛙的体细胞超突变机制。
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