Turner R
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institute of Health, Bethesda, MD 20892.
Am J Physiol Imaging. 1992 Jul-Dec;7(3-4):136-45.
New techniques for imaging of brain function are described, which utilize magnetic resonance imaging. Echo-planar imaging (EPI), the preferred method, is introduced and technical issues are discussed. Two recent approaches for measurement of blood flow are explained: contrast agent bolus tracking and black blood perfusion. An intrinsic contrast technique, which utilizes the paramagnetism of deoxyhemoglobin, is presented. Results from experiments on functional imaging of the human brain are shown, and the specific advantages of MRI for this purpose are discussed.
描述了用于脑功能成像的新技术,这些技术利用磁共振成像。介绍了首选方法——回波平面成像(EPI)并讨论了技术问题。解释了两种最近用于测量血流的方法:造影剂团注追踪和黑血灌注。提出了一种利用脱氧血红蛋白顺磁性的固有对比技术。展示了人脑功能成像实验的结果,并讨论了MRI在此方面的具体优势。