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[心内膜心肌活检标本中检测到多核巨细胞的心脏结节病:3例报告]

[Cardiac sarcoidosis with multinucleated giant cells detected in endomyocardial biopsy specimens: report of 3 cases].

作者信息

Sakoda S, Fukuhara T, Mitsunami K, Kinoshita M

机构信息

First Department of Internal Medicine, Shiga University of Medical Science, Ohtsu.

出版信息

J Cardiol. 1992;22(4):731-8.

PMID:1343640
Abstract

This is a report of 3 cases of cardiac sarcoidosis. None of the 3 patients had other overt systemic involvement. Multinucleated giant cells and non-caseating epithelial cell granulomas with small lymphocytic infiltrations were detected in the endomyocardial biopsy specimen. Some focal left ventricular wall motion abnormalities were detected by echocardiography and angiography in all 3 patients. Paroxysmal ventricular tachycardia and multifocal ventricular premature complexes were observed by Holter 24-hour electrocardiography in all 3 patients. Two of the 3 patients did not receive corticosteroids, but remaining patient is on a regimen of corticosteroid.

摘要

本文报告3例心脏结节病。3例患者均无其他明显的全身受累情况。心内膜活检标本中检测到多核巨细胞和非干酪样上皮细胞肉芽肿伴小淋巴细胞浸润。所有3例患者经超声心动图和血管造影均检测到一些局灶性左心室壁运动异常。所有3例患者经24小时动态心电图监测均观察到阵发性室性心动过速和多源性室性早搏。3例患者中有2例未接受皮质类固醇治疗,其余1例患者正在接受皮质类固醇治疗方案。

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