Bye A M, Nunan J
Prince of Wales Children's Hospital, Sydney.
Clin Exp Neurol. 1992;29:92-8.
Over a 3 year period 186 children aged 3 weeks to 17 years were studied by telemetry (prolonged video and EEG monitoring) at the Prince of Wales Children's Hospital: 74 had events considered at referral to possibly represent seizures but which were shown by clinical analysis and telemetry to be non-ictal. Nine such patients were developmentally delayed, one was neurologically impaired and 16 were both developmentally delayed and neurologically impaired. A specific diagnosis of the non-ictal events was reached in 24 subjects-postures of spasticity in children with neurological impairment (6), Münchausen-by-proxy (5), pseudoseizures (3), breathholding (2), masturbation (2), reflux (2), shudder (1), movement disorder (1), motor tic (1) and pertussis (1). Specific descriptive patterns were assigned to the remaining 51 events. These included staring (20) and jerks (16) or unusual behaviour (15). 49 inter-event EEGs were normal; 7 displayed abnormal background rhythms and 19 showed epileptiform activity. We discourage use of the term 'pseudoseizure' for the majority of the events described and prefer that a specific diagnosis be made or a descriptive analysis be provided. The events seen illustrate the wide spectrum of childhood behaviour and on occasions suggest the need for telemetry to determine their true nature.
在3年的时间里,威尔士王子儿童医院对186名年龄在3周至17岁的儿童进行了遥测研究(长时间视频和脑电图监测):74名儿童在转诊时被认为可能有癫痫发作,但经临床分析和遥测显示为非癫痫性发作。其中9名患者有发育迟缓,1名有神经功能障碍,16名既有发育迟缓又有神经功能障碍。24名受试者的非癫痫性发作得到了明确诊断——神经功能障碍儿童的痉挛姿势(6例)、代理孟乔森综合征(5例)、假性癫痫发作(3例)、屏气发作(2例)、手淫(2例)、反流(2例)、颤抖(1例)、运动障碍(1例)、运动性抽搐(1例)和百日咳(1例)。其余51例发作被赋予了特定的描述性模式。这些包括凝视(20例)、抽搐(16例)或异常行为(15例)。49次发作间期脑电图正常;7次显示背景节律异常,19次显示癫痫样活动。对于所描述的大多数发作,我们不鼓励使用“假性癫痫发作”这个术语,而建议做出明确诊断或提供描述性分析。所观察到的发作说明了儿童行为的广泛范围,有时表明需要进行遥测以确定其真实性质。