Parise E R, Leite-Mór M M, Rosa H
Disciplina de Gastroenterologia Clínica, Escola Paulista de Medicina, São Paulo, Brasil.
Mem Inst Oswaldo Cruz. 1992;87 Suppl 4:127-8. doi: 10.1590/s0074-02761992000800018.
Serum laminin level was measured in chronic hepatic schistosomiasis. A significant increase in the mean serum laminin levels was observed in patients with hepatosplenic (HS) schistosomiasis (2.57 +/- 0.83 U/ml), as compared to those in patients with the hepatointestinal (HI) form of the disease (1.38 +/- 0.45-U/ml) and in the control group (1.15 +/- 0.31 U/ml). In the HS patients there was a significant direct relation between serum laminin and percutaneous splenic pulp pressure (r = 0.68). These findings are compatible with an increased production of laminin in hepatosplenic schistosomiasis with may be related to the observed enlarged liver and spleen basement membranes in such disease.
对慢性肝血吸虫病患者的血清层粘连蛋白水平进行了检测。观察到肝脾型（HS）血吸虫病患者的平均血清层粘连蛋白水平显著升高（2.57±0.83 U/ml），而肝肠型（HI）血吸虫病患者（1.38±0.45 U/ml）和对照组（1.15±0.31 U/ml）的该水平则较低。在HS患者中，血清层粘连蛋白与经皮脾髓压之间存在显著的正相关（r = 0.68）。这些发现与肝脾型血吸虫病中层粘连蛋白产生增加相一致，这可能与该疾病中观察到的肝脏和脾脏基底膜增大有关。
