家兔心脏闰盘胚胎学的电子显微镜研究。
An electron microscope study of the embryology of the intercalated disc in the heart of the rabbit.
作者信息
MUIR A R
出版信息
J Biophys Biochem Cytol. 1957 Mar 25;3(2):193-202. doi: 10.1083/jcb.3.2.193.
Abstract
Prenatal and postnatal cardiac muscle from rabbits has been studied by electron microscopy, after osmium fixation and methacrylate embedding. The observations showed that 1. Cell membranes divide the muscle into cellular units from the youngest embryo which was studied (9(1/2) days after coitus) until the adult state. 2. The embryonic muscle cells contain only one nucleus, whereas the adult cell may be multinucleated. 3. At all stages of development, wherever a myofibrillar axis crosses a cellular boundary, the myofilaments are interrupted by an intercalated disc. 4. With age, increase in size and complexity of the discs render them recognisable by the light microscope.
摘要
通过锇固定和甲基丙烯酸酯包埋后，利用电子显微镜对兔的产前和产后心肌进行了研究。观察结果表明：1. 从所研究的最早期胚胎（交配后9(1/2)天）到成年状态，细胞膜将肌肉分隔成细胞单位。2. 胚胎肌细胞仅含有一个细胞核，而成体细胞可能是多核的。3. 在发育的所有阶段，只要肌原纤维轴穿过细胞边界，肌丝就会被闰盘中断。4. 随着年龄的增长，闰盘的大小和复杂性增加，使其在光学显微镜下可识别。
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