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[曼氏血吸虫病低度传播地区的控制]

[Control of schistosomiasis mansoni in an area of low transmission].

作者信息

Dias L C, Marçal Júnior O, Glasser C M, Kanamura H Y, Hotta L K

机构信息

Instituto de Biologia, Universidade Estadual de Campinas, SP, Brasil.

出版信息

Mem Inst Oswaldo Cruz. 1992;87 Suppl 4:233-9. doi: 10.1590/s0074-02761992000800036.

Abstract

The schistosomiasis is transmitted by Biomphalaria tenagophila in our study area (Pedro de Toledo, São Paulo, Brazil). From 1980 to 1990 epidemiological surveys in a population of 4,000 inhabitants, has shown that: prevalences by Kato-Katz (KKT), immunofluorescence (FT) and intradermal (IDT) techniques were 22.8%, 55.5% and 51.8%, respectively; intensity of infection was low, 58.5 eggs per gram of faeces (epg); there were no symptomatic cases; prevalences were higher in mates, children and rural zone; index of potential contamination was 57.5% in the age group 5 to 20 years; 2/3 of patients were autochthonous; cases were no-randomly aggregated; transmission was focal and only 0.4% of snails were infected; water contacts through recreation showed the most important odds ratio; knowledge, attitudes and practices were satisfactory. From the epidemiological findings a control programme was carried out: yearly faeces exams, chemotherapy, molluscocide, health education and sanitation. Thus, the prevalence decreased sharply to 3.3% and intensity of infection to 30.3 epg; the incidence rates ranged between 0.4% and 2.5% annually; the sanitation became better and the youngsters were the main target in prophylaxis. To improve control, immunodiagnosis has to be conducted and the involvement of the population should be increase. However, we cannot forget that re-infection, therapeutic failure, etc, could play a major role in the maintenance this residual prevalence.

摘要

在我们的研究区域(巴西圣保罗州佩德罗·德·托莱多),血吸虫病由嗜眼扁卷螺传播。1980年至1990年期间,对4000名居民进行的流行病学调查显示:加藤厚涂片法(KKT)、免疫荧光法(FT)和皮内试验(IDT)的患病率分别为22.8%、55.5%和51.8%;感染强度较低,每克粪便中有58.5个虫卵(epg);无有症状病例;男性、儿童和农村地区的患病率较高;5至20岁年龄组的潜在污染指数为57.5%;三分之二的患者为本地病例;病例呈非随机聚集;传播为局部性,仅0.4%的蜗牛受到感染;通过娱乐活动接触水显示出最重要的优势比;知识、态度和行为令人满意。根据流行病学调查结果实施了一项控制计划:每年进行粪便检查、化疗、灭螺、健康教育和环境卫生改善。因此,患病率急剧下降至3.3%,感染强度降至30.3 epg;发病率每年在0.4%至2.5%之间;环境卫生得到改善,年轻人是预防的主要目标。为了加强控制,必须进行免疫诊断并提高人群的参与度。然而,我们不能忘记,再感染、治疗失败等因素可能在维持这种残余患病率方面发挥重要作用。

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