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欧加农试剂盒与杜邦试剂盒在通过免疫印迹法对献血者血清中HIV感染进行确证性血清学检测方面的相对性能。

Relative performance of Organon kit in comparison to Du Pont for confirmatory serological testing of HIV infection by western blot test in sera from blood donors.

作者信息

Aggarwal R K, Chatterjee R, Chattopadhya D, Kumari S

机构信息

National Institute of Communicable Diseases, Sham Nath Marg, Delhi.

出版信息

J Commun Dis. 1992 Jun;24(2):78-81.

PMID:1344175
Abstract

A total of 32 specimens with different categories of reactivity by Du Pont Western Blot kit comprising of specimens showing full spectrum of HIV-I antigen specific bands, 19 specimens showing total absence of bands and four specimens showing non-specific bands (without any interpretative importance) were subjected to Western Blot testing by Organon test. Of the nine specimens showing full spectrum of bands by Du Pont the correlation with Organon kit was 100 per cent based on WHO criteria. Four specimens with non-specific indeterminate band pattern by Du Pont failed to show any band in Organon kit, indicating that latter to be more specific.

摘要

共有32个样本,用杜邦蛋白质免疫印迹试剂盒检测时呈现不同类型的反应性,包括显示出HIV-I抗原特异性条带全谱的样本、19个完全没有条带的样本以及4个显示非特异性条带(无任何解释意义)的样本,这些样本接受了欧加农检测试剂盒的蛋白质免疫印迹检测。在杜邦试剂盒检测显示条带全谱的9个样本中,根据世界卫生组织标准,与欧加农试剂盒的相关性为100%。杜邦试剂盒检测呈现非特异性不确定条带模式的4个样本,在欧加农试剂盒检测中未显示任何条带,这表明后者更具特异性。

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