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[原发性脑干病变患者的多模态诱发电位和瞬目反射]

[Multimodal evoked potentials and the blink reflex in patients with primary brainstem lesions].

作者信息

Durić S, Klopcic-Spevak M

机构信息

Neuroloska klinika Univerzitetskog klinickog centra u Nisu.

出版信息

Med Pregl. 1992;45(11-12):432-6.

PMID:1344443
Abstract

In 17 patients with primary brainstem injury, out of 60 patients with severe head trauma, diagnostic and prognostic values of multimodal evoked potentials and blink reflex were evaluated in relation to clinical syndromes of the brainstem, the duration of coma and the outcome. Clinical classification of the brainstem syndromes according to Gerstenbrand and Rumpl was used for the evaluation of the clinical findings, the Innsbruck Coma Scale (ICS) for the evaluation of the coma level, and the Glasgow Outcome Scale (GOS) for the outcome. Analyses and measurements of the multimodal evoked potentials and blink reflex were used many times in the period of assessment (six months after the injury). The analysis of our results with multimodal evoked potentials and blink reflex revealed different correlation and sensitivity in relation to the clinical syndromes of the brainstem, the duration of coma and the outcome of the injury. The blink reflex and somatosensory evoked potentials had the best correlation and the greatest sensitivity, the auditory evoked potentials had somewhat, while the visual evoked potentials had none. Multimodal evoked potentials and blink reflex increase the specificity of the diagnosis of brainstem injury compared to clinical observation only, and improve prognostic reliability.

摘要

在60例重度颅脑损伤患者中,选取17例原发性脑干损伤患者,评估多模态诱发电位和瞬目反射对于脑干临床综合征、昏迷持续时间及预后的诊断和预后价值。采用Gerstenbrand和Rumpl的脑干综合征临床分类法评估临床发现,采用因斯布鲁克昏迷量表(ICS)评估昏迷程度,采用格拉斯哥预后量表(GOS)评估预后。在评估期间(受伤后6个月)多次进行多模态诱发电位和瞬目反射的分析与测量。对多模态诱发电位和瞬目反射结果的分析显示,其与脑干临床综合征、昏迷持续时间及损伤预后的相关性和敏感性各异。瞬目反射和体感诱发电位的相关性最佳、敏感性最高,听觉诱发电位的相关性和敏感性一般,而视觉诱发电位则无相关性。与仅进行临床观察相比,多模态诱发电位和瞬目反射提高了脑干损伤诊断的特异性,并改善了预后可靠性。

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