Riffel B, Stöhr M, Graser W, Trost E, Baumgärtner H
Neurologische Klinik mit Klinischer Neurophysiologie, Zentralklinikum Augsburg.
Anaesthesist. 1989 Feb;38(2):51-8.
During 72 h following severe head injury, 103 patients in acute posttraumatic coma were assessed by clinical examinations (documented by Glasgow Coma Score) and brain stem auditory evoked potentials (BAEP) as well as short-latency somatosensory evoked potentials (SEP) following median-nerve stimulation. Patient outcomes were classified at 6 months or more according to the following categories: good recovery, severely disabled or vegetative, and brain dead. Patients who had died of systemic complications (pneumonia, septicemia, renal failure, etc.) were excluded from the study. The Glasgow Coma Score was reliable in forecasting a favorable outcome; all patients with a Score over 9 points had a good recovery. The Glasgow Coma Score was not reliable in predicting an unfavorable outcome, however; some patients with the lowest possible Glasgow Coma Score (3 points) at the early clinical examination survived with good recovery. The BAEPs were reliable predictors of an unfavorable outcome; the outcome was unfavorable when a missing wave V or more missing waves pointed toward a secondary brainstem lesion. Normal BAEPs were not reliable, however, in predicting a favorable outcome. SEP data served as a prognostic indicator of unfavorable as well as favorable outcomes. In summary, evoked potentials add valuable information to the clinical examination in assessing a patient's outcome after severe head injury.
在重度颅脑损伤后的72小时内,对103例急性创伤后昏迷患者进行了临床检查(以格拉斯哥昏迷评分记录)、脑干听觉诱发电位(BAEP)以及正中神经刺激后的短潜伏期体感诱发电位(SEP)评估。根据以下类别在6个月或更长时间后对患者预后进行分类:恢复良好、重度残疾或植物状态以及脑死亡。死于全身并发症(肺炎、败血症、肾衰竭等)的患者被排除在研究之外。格拉斯哥昏迷评分在预测良好预后方面是可靠的;所有评分超过9分的患者都恢复良好。然而,格拉斯哥昏迷评分在预测不良预后方面并不可靠;一些在早期临床检查中格拉斯哥昏迷评分最低(3分)的患者存活下来并恢复良好。BAEP是不良预后的可靠预测指标;当V波缺失或更多波缺失提示继发性脑干病变时,预后不良。然而,正常的BAEP在预测良好预后方面并不可靠。SEP数据可作为不良和良好预后的预后指标。总之,诱发电位在评估重度颅脑损伤患者的预后时,为临床检查增添了有价值的信息。