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[儿童尾侧神经孔闭合不全畸形中脊柱病变的临床表现]

[Clinical manifestations of spinal lesions in dysraphic malformations of the caudal neuropore in children].

作者信息

Borisev V, Spevak M, Varga J

机构信息

Institut za zdravstvenu zastitu majke i deteta, Novi Sad.

出版信息

Med Pregl. 1992;45(7-8):294-6.

PMID:1344462
Abstract

Disorders in the development of the spine and the spinal cord in the caudal neuroporus region significantly contribute to the morbidity and the lasting invalidity of children. Clinical investigations of the malformations manifest through different forms of body abnormalities, ranging from asymptomatic forms of "spina bifida occultae" to the severe forms of open "meningomyelocele". The nature and the level often cannot be detected before the development of the structural changes in the course of growth and development of the child, which can hardly be treated later. At the Department of Child Surgery in Novi Sad 12 infants were surgically treated in the last 5 years, while 30 children were surgically and conservatively treated after the detection of the clinical and subclinical manifestations of dysraphism. The indications for the surgical treatment were open meningomyelocele as well as those subclinical forms indicating the development of the tethered corn syndrome, hydrocephalus and tumefactions in the lumbosacral region. Moreover the study points to the significance of certain clinical features and investigations in the diagnosis of spinal dysraphism.

摘要

尾侧神经管区域脊柱和脊髓发育异常是导致儿童发病和长期残疾的重要原因。畸形的临床症状表现为各种身体异常,从无症状的“隐性脊柱裂”到严重的开放性“脊髓脊膜膨出”。在儿童生长发育过程中,往往在结构变化出现之前无法检测到畸形的性质和程度,而后期治疗难度很大。在诺维萨德儿童外科,过去5年有12名婴儿接受了手术治疗,另有30名儿童在发现脊髓发育异常的临床和亚临床症状后接受了手术及保守治疗。手术治疗的指征包括开放性脊髓脊膜膨出以及那些提示存在脊髓拴系综合征、脑积水和腰骶部肿物等亚临床症状。此外,该研究还指出了某些临床特征和检查在脊髓发育异常诊断中的重要性。

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