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[豚鼠乙氧苯唑酸致聋后经微波治疗缓解]

[Deafness, induced by sodium ethacrynate in guinea pigs, alleviated by microwave treatment].

作者信息

Chen X M, Din D L, Luo D F, Huangfu M S, Jin X M

机构信息

Hôpital Renji, Université Médicale de Shanghai II, Service O.R.L., R.P. de Chine.

出版信息

Rev Laryngol Otol Rhinol (Bord). 1992;113(2):133-5.

PMID:1344522
Abstract

Microwave is used to treat temporal hearing loss caused by intravenous injection of the ethacrynic acid in guinea pigs. The recovery of hearing is much faster in the treated groups than in the control group. The article proposes possible mechanism of the effects against the ethacrynic acid induced deafness and assume that the result of this research can provide an experimental basis for treatment of some perceptive deafness due to ischemia of stria vascularis of the cochlea.

摘要

微波被用于治疗豚鼠因静脉注射依他尼酸所致的暂时性听力损失。治疗组的听力恢复比对照组快得多。本文提出了针对依他尼酸所致耳聋的可能作用机制,并认为本研究结果可为治疗某些因耳蜗血管纹缺血引起的感音性耳聋提供实验依据。

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The ototoxic effects of ethacrynic acid in man and animals.
Laryngoscope. 1976 Aug;86(8):1065-86. doi: 10.1288/00005537-197608000-00001.

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