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[豚鼠乙氧苯唑酸致聋后经微波治疗缓解]

[Deafness, induced by sodium ethacrynate in guinea pigs, alleviated by microwave treatment].

作者信息

Chen X M, Din D L, Luo D F, Huangfu M S, Jin X M

机构信息

Hôpital Renji, Université Médicale de Shanghai II, Service O.R.L., R.P. de Chine.

出版信息

Rev Laryngol Otol Rhinol (Bord). 1992;113(2):133-5.

PMID:1344522
Abstract

Microwave is used to treat temporal hearing loss caused by intravenous injection of the ethacrynic acid in guinea pigs. The recovery of hearing is much faster in the treated groups than in the control group. The article proposes possible mechanism of the effects against the ethacrynic acid induced deafness and assume that the result of this research can provide an experimental basis for treatment of some perceptive deafness due to ischemia of stria vascularis of the cochlea.

摘要

微波被用于治疗豚鼠因静脉注射依他尼酸所致的暂时性听力损失。治疗组的听力恢复比对照组快得多。本文提出了针对依他尼酸所致耳聋的可能作用机制,并认为本研究结果可为治疗某些因耳蜗血管纹缺血引起的感音性耳聋提供实验依据。

相似文献

1
[Deafness, induced by sodium ethacrynate in guinea pigs, alleviated by microwave treatment].[豚鼠乙氧苯唑酸致聋后经微波治疗缓解]
Rev Laryngol Otol Rhinol (Bord). 1992;113(2):133-5.
2
[Experimental study on the therapeutic value of microwave on hearing loss due to ethacrynic acid ototoxicity].[微波对依他尼酸耳毒性所致听力损失治疗价值的实验研究]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1993;28(4):225-7, 252.
3
The ototoxic effects of ethacrynic acid in man and animals.
Laryngoscope. 1976 Aug;86(8):1065-86. doi: 10.1288/00005537-197608000-00001.
4
Freeze-fracture studies of the stria vascularis following administration of ethacrynic acid to guinea pigs.
Scand Audiol Suppl. 1981;14 Suppl:173-83.
5
[Electron microscopic study on changes of the stria vascularis induced by ethacrynic acid].[依他尼酸所致血管纹变化的电镜研究]
Nihon Jibiinkoka Gakkai Kaiho. 1973 Mar;76(3):338-46.
6
[Functional morphology of stria vascularis after treatment with ethacrynic acid or atoxyl (author's transl)].依他尼酸或阿砜那明治疗后血管纹的功能形态学(作者译)
Arch Otorhinolaryngol. 1978 Jan 30;218(3-4):179-90.
7
Comparison of the effects of furosemide and ethacrynic acid upon the cochlear function in the guinea pig.
Scand Audiol Suppl. 1981;14 Suppl:63-9.
8
Effect of loop-diuretics on hair cells of the cochlea in guinea pigs. Histological and histochemical study.
Scand Audiol Suppl. 1981;14 Suppl:185-99.
9
[Electron microscopic observation of the changes in the cochlear duct caused by administration of ethacrynic acid, with special reference to the changes in the stria vascularis].[依他尼酸给药引起耳蜗管变化的电子显微镜观察,特别关注血管纹的变化]
Nihon Jibiinkoka Gakkai Kaiho. 1972 Oct;75(10):1019-21.
10
Ototoxicity of ethacrynic acid (a persistent clinical problem).依他尼酸的耳毒性(一个持续存在的临床问题)。
J Laryngol Otol. 1988 Jun;102(6):518-20. doi: 10.1017/s0022215100105523.

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1
Ototoxic effects and mechanisms of loop diuretics.袢利尿剂的耳毒性作用及机制。
J Otol. 2016 Dec;11(4):145-156. doi: 10.1016/j.joto.2016.10.001. Epub 2016 Oct 27.