Alvarez Bernal L P, Martínez Machín G, Fernández Andreu C, Llop Hernández A
Laboratorio de Micología, Instituto de Medicina Tropical Pedro Kourí.
Rev Cubana Med Trop. 1992;44(1):29-33.
A latex reactive was designed for detecting Cryptococcus neoformans antigen. It was evaluated by a comparative study with a commercial system (Meridian Diagnostic, Inc.). Total coincidence was observed with both latex systems after studying 3 sample groups: patients with cryptococcosis diagnosis, blood bank donors and patients with clinical signs of the disease. Sensitivity, specificity and stability of the latex reactives prepared were assessed. This diagnostic technique opens new perspectives for quick diagnosis in Cuba, especially for immunosuppressed patients. It will allow for timely treatment and at the same time will contribute to saving expenses in imports.
设计了一种用于检测新型隐球菌抗原的乳胶试剂。通过与商业系统（子午线诊断公司）进行比较研究对其进行了评估。在研究了3个样本组后，观察到两种乳胶系统的总符合率：确诊为隐球菌病的患者、血库献血者以及有该疾病临床症状的患者。对所制备的乳胶试剂的敏感性、特异性和稳定性进行了评估。这种诊断技术为古巴的快速诊断开辟了新的前景，特别是对于免疫抑制患者。它将有助于及时治疗，同时有助于节省进口费用。
