Hennekam R C, Baselier A C, Beyaert E, Bos A, Blok J B, Jansma H B, Thorbecke-Nilsen V V, Veerman H
Clinical Genetics Center, Utrecht, The Netherlands.
Am J Ment Retard. 1992 May;96(6):645-60.
Forty individuals with Rubinstein-Taybi syndrome were tested using an extensive test battery to obtain more insight about their intelligence level, social competency, temperament, and behavior as well as articulation and receptive and expressive language level. Examination of individuals in the Netherlands who have this rare syndrome has been extensive, allowing some generalizations to be made. The intelligence level of affected individuals is usually low, although some persons have much higher scores than do others. The tested individuals were remarkably consistent in their social competency, temperament, and behavior. They were able to make good use of their limited verbal abilities. Comparable studies of other groups of persons with a specific syndrome are needed to determine whether the present findings are specific for Rubinstein-Taybi syndrome or may be found among persons with other syndromes.
对40名患有鲁宾斯坦-泰比综合征的个体进行了一系列广泛的测试，以更深入地了解他们的智力水平、社交能力、气质和行为，以及发音、接受性和表达性语言水平。在荷兰对患有这种罕见综合征的个体进行的检查范围广泛，从而可以得出一些一般性结论。受影响个体的智力水平通常较低，不过有些人的得分比其他人高得多。接受测试的个体在社交能力、气质和行为方面表现出显著的一致性。他们能够充分利用自己有限的语言能力。需要对其他特定综合征患者群体进行类似研究，以确定目前的发现是鲁宾斯坦-泰比综合征所特有的，还是在其他综合征患者中也可能出现。
