Ramaiah K D, Das P K, Arunachalam N, Rajavel A R, Paily K P
Vector Control Research Centre (Indian Council of Medical Research) Indira Nagar, Medical Complex, Pondicherry.
J Commun Dis. 1992 Sep;24(3):173-84.
An Integrated Vector Management strategy, implemented as an alternative to the conventional control operations that include mainly chemical control in Pondicherry, South India, reduced very substantially the population density of Culex quinquefasciatus. This resulted in drastic decrease in the intensity of transmission of bancroftian filariasis transmitted by Culex quinquefasciatus and consequently the incidence of new infections in children of 0-5 age group was minimized. When the IVM strategy was withdrawn after five years of implementation and conventional control measures were re-adopted, resilience of Culex quinquefasciatus population was observed and human exposure to the risk of infection increased. The results suggest that maintenance of vector density at reduced levels for prolonged periods, is necessary to control infectious diseases like filariasis, which is difficult in the present day urban situations in developing countries. Hence the emphasis should be on chemotherapy to achieve control of lymphatic filariasis.
在印度南部本地治里实施的综合病媒管理策略，作为主要包括化学防治在内的传统防治行动的替代方案，极大地降低了致倦库蚊的种群密度。这导致由致倦库蚊传播的班氏丝虫病传播强度大幅下降，因此0至5岁儿童新感染病例的发生率降至最低。在实施五年后撤销综合病媒管理策略并重新采用传统防治措施时，观察到致倦库蚊种群具有恢复能力，且人类感染风险增加。结果表明，长期将病媒密度维持在较低水平对于控制丝虫病等传染病是必要的，而这在发展中国家当今的城市环境中很难实现。因此，应重点依靠化疗来控制淋巴丝虫病。
