Das P K, Manoharan A, Subramanian S, Ramaiah K D, Pani S P, Rajavel A R, Rajagopalan P K
Vector Control Research Centre (Indian Council of Medical Research, Indira Nagar, Pondicherry.
Epidemiol Infect. 1992 Jun;108(3):483-93. doi: 10.1017/s0950268800049992.
An Integrated Vector Management (IVM) strategy was implemented from 1981 to 1985 in one part of Pondicherry, South India, for the control of the bancroftian filariasis vector Culex quinquefasciatus (the IVM area). The rest of the town (the comparison area) received the conventional larvicidal input. After 1985 both the areas were managed conventionally. The switch to conventional strategy resulted in an increase of vector density in both areas. The microfilaraemia prevalence in humans showed a general decline (P less than 0.05) from 1986 to 1989 only in the IVM area whereas its intensity did not change significantly in either area. While the age-specific rate of gain of infection was generally unchanged in the IVM area, an increase in all age classes was observed after 1985 in the comparison area, where the Annual Transmission Index was high during the previous years. In both areas the rate of loss of infection increased during 1986-9 compared to 1981-6. The results suggest that 3 years is too short a period to relate the changes in entomological parameters to those in the microfilaraemia status of the population.
1981年至1985年期间，在印度南部本地治里的一个区域实施了综合病媒管理（IVM）策略，以控制班氏丝虫病病媒致倦库蚊（IVM区域）。该镇的其他区域（对照区域）接受常规的杀幼虫投入。1985年之后，两个区域均采用常规管理。转向常规策略导致两个区域的病媒密度均增加。仅在IVM区域，1986年至1989年期间人类微丝蚴血症患病率总体呈下降趋势（P<0.05），而两个区域的微丝蚴血症强度均无显著变化。虽然IVM区域特定年龄的感染获得率总体未变，但在对照区域，1985年之后所有年龄组均出现增加，该区域在前几年的年传播指数较高。与1981年至1986年相比，1986年至1989年期间两个区域的感染消失率均有所增加。结果表明，将昆虫学参数的变化与人群微丝蚴血症状况的变化联系起来，3年的时间太短。
