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子宫颈癌患者循环多形核白细胞的吞噬活性。

Phagocytic activity of circulating polymorphonuclear leukocytes from patients with carcinoma of the uterine cervix.

作者信息

García-González J E, Rojas-Espinosa O, Aguilar-Santelises M

机构信息

Departamento de Immunología, Escuela Nacional de Ciencias Biológicas, I.P.N., México, D.F., México.

出版信息

Rev Latinoam Microbiol. 1992 Apr-Jun;34(2):135-41.

PMID:1345310
Abstract

Peripheral blood leukocytes and the sera from 10 healthy women and 12 patients with invasive carcinoma of the cervix (stages I to IV), showed no differences in their capacity to inhibit the replication of an invasive strain of Escherichia coli. The serum from only one patient was unable to arrest the bacterial growth. The quantitation of myeloperoxidase in the polymorphonuclear leukocytes from 21 patients (stages I to III) and 11 healthy women showed, however, a lower activity in the group of patients (P = 0.001). Most patients also showed lymphocytopenia, neutrophilia, and eosinophilia but normal counts of total leukocytes.

摘要

10名健康女性和12名浸润性宫颈癌患者(I至IV期)的外周血白细胞和血清,在抑制大肠杆菌侵袭菌株复制的能力上没有差异。只有一名患者的血清无法阻止细菌生长。然而,对21名患者(I至III期)和11名健康女性的多形核白细胞中的髓过氧化物酶进行定量分析显示,患者组的活性较低(P = 0.001)。大多数患者还表现出淋巴细胞减少、中性粒细胞增多和嗜酸性粒细胞增多,但白细胞总数正常。

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Rev Latinoam Microbiol. 1992 Apr-Jun;34(2):135-41.
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