Mattsby-Baltzer I, Mobacken H, Olling S, Rosén K
Acta Derm Venereol. 1978;58(6):494-6.
The phagocytic bactericidal capacity of circulating neutrophilic granulocytes was estimated in 22 patients with pustulosis palmoplantaris (PPP). The control group comprised 100 healthy individuals. Leukocytes from the patients had a statistically significant reduced capacity to kill Staph. aureus in autologous as well as in AB serum. Leukocyte killing of E. coli was not reduced. Serum levels of total hemolytic complement, C3, C4 and neutrophil myeloperoxidase activity were normal. The findings suggest an intrinsic or cellular defect of circulating neutrophil granulocytes in patients with PPP.
对22例掌跖脓疱病（PPP）患者循环中性粒细胞的吞噬杀菌能力进行了评估。对照组由100名健康个体组成。患者的白细胞在自身血清以及AB血清中杀灭金黄色葡萄球菌的能力在统计学上显著降低。对大肠杆菌的白细胞杀伤能力未降低。总溶血补体、C3、C4的血清水平及中性粒细胞髓过氧化物酶活性均正常。这些发现提示掌跖脓疱病患者循环中性粒细胞存在内在或细胞缺陷。
