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[在阿根廷共和国米西奥内斯省波萨达斯市开展的一项研究中对婴儿腹泻中的肠道病原体进行鉴定]

[Identification of enteropathogens in infantile diarrhea in a study performed in the city of Posadas, Misiones, República Argentina].

作者信息

Vergara M, Quiroga M, Grenón S, Villalba V, Pegels E, Chade M, González C, Binsztein N, Eiguer T, Depetris A

机构信息

Cátedra de Bacteriología, Facultad de Ciencias Exactas, Químicas y Naturales, Universidad Nacional de Misiones, Posadas, República Argentina.

出版信息

Rev Latinoam Microbiol. 1992 Apr-Jun;34(2):71-5.

PMID:1345313
Abstract

The following work informs of the results of isolation, frequency and distribution of enteropathogens in children under five years old, without previous antibiotic treatment, less than seven days with diarrhoea, ambulatory or in Hospital "Dr. Ramón Madariaga" de Posadas, Misiones, República Argentina, from June 1986 to May 1989. From a total of 972 children with diarrhoea, 78% required to be hospitalized. The greatest number of cases were found during spring and summer in children from 1 to 11 months of age. Distribution of the main enteropathogens was: enteropathogenic Escherichia coli (EPEC) (29.4%), parasites (22%), Shigella (16.3%), enterotoxigenic Escherichia coli (ETEC) (14%) and rotavirus (12.9%). Highest incidence of rotavirus was registered in the coldest months and Shigella, ETEC, Salmonella and parasites in the warm months. The group of most affected children were from 1 to 11 months of age, with higher incidence of EPEC, Salmonella and rotavirus, and parasites were found in older children. ETEC and Shigella had no relationship with the age of children. The most frequent association was EPEC with rotavirus. This is the first finding of Salmonella zaiman in humans and of Salmonella hadar in Argentina. Cryptosporidium, etiological agent of serious diarrhoea in the immunocompetent, was isolated in 3.9% of our cases.

摘要

以下研究报告了1986年6月至1989年5月期间,在阿根廷米西奥内斯省波萨达斯市“拉蒙·马达里亚加医生”医院门诊或住院的5岁以下、未接受过抗生素治疗、腹泻病程少于7天的儿童中肠道病原体的分离情况、频率及分布。在总共972例腹泻儿童中,78%需要住院治疗。病例数最多的是1至11个月大的儿童,且集中在春季和夏季。主要肠道病原体的分布情况为:致病性大肠杆菌(EPEC)(29.4%)、寄生虫(22%)、志贺氏菌(16.3%)、产毒性大肠杆菌(ETEC)(14%)和轮状病毒(12.9%)。轮状病毒发病率最高的月份是最冷的月份,而志贺氏菌、ETEC、沙门氏菌和寄生虫发病率最高的月份是温暖的月份。受影响最大的儿童群体是1至11个月大,EPEC、沙门氏菌和轮状病毒发病率较高,而寄生虫多见于年龄较大的儿童。ETEC和志贺氏菌与儿童年龄无关。最常见的关联是EPEC与轮状病毒。这是人类首次发现扎伊曼沙门氏菌以及阿根廷首次发现哈达尔沙门氏菌。隐孢子虫是免疫功能正常者严重腹泻的病原体,在我们3.9%的病例中被分离出来。

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