氢化链霉菌生长及20β-羟基类固醇脱氢酶诱导过程中的核苷三磷酸水平
Nucleoside triphosphate levels in Streptomyces hydrogenans during growth and induction of 20beta-hydroxysteroid dehydrogenase.
作者信息
Betz J, Träger L
出版信息
Z Naturforsch C Biosci. 1976 Jul-Aug;31(7-8):486-7. doi: 10.1515/znc-1976-7-828.
PMID:134589
Abstract
Levels of the purine nucleoside triphosphates are decreasing towards the end of log phase growth of Streptomyces hydrogenans. Induction of 20beta-hydroxysteroid dehydrogenase by addition of 11beta,21-dihydroxy-4,17(20)-pregnadien-3-one to the growth medium leads to a pronounced drop in purine nucleoside triphosphate levels with is irreversible in contrast to the initial loss and later accumulation of RNA.
摘要
在氢化链霉菌对数生长期末期，嘌呤核苷三磷酸的水平在下降。向生长培养基中添加11β,21-二羟基-4,17(20)-孕二烯-3-酮诱导20β-羟基类固醇脱氢酶，会导致嘌呤核苷三磷酸水平显著下降，这与RNA最初的减少及随后的积累不同，是不可逆的。
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