[L-亮氨酸过载对糖尿病大鼠游离氨基酸水平的影响]
[Influence of L-leucine overloading on the level of free amino acids in the diabetic rat].
作者信息
Grizard J, Maciejewska M, Prugnaud J, Pion R
出版信息
C R Seances Soc Biol Fil. 1976;170(1):103-11.
PMID:134759
Abstract
Alloxan injection in the rat results in a large increase of branched free amino acids (leucine, isoleucine, valine) in the blood, liver and muscle; it decreases most of the non essential free amino acids in liver. L-leucine administration in the diabetic rat results in a large decrease of plasma corticosterone. It increases free leucine but decreases free isoleucine and valine in blood and muscle. It decreases most of the essential free amino acids in liver.
摘要
给大鼠注射四氧嘧啶会导致血液、肝脏和肌肉中支链游离氨基酸（亮氨酸、异亮氨酸、缬氨酸）大幅增加；它会降低肝脏中大多数非必需游离氨基酸的含量。给糖尿病大鼠施用L-亮氨酸会导致血浆皮质酮大幅降低。它会增加血液和肌肉中的游离亮氨酸，但会降低游离异亮氨酸和缬氨酸的含量。它会降低肝脏中大多数必需游离氨基酸的含量。
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[Influence of L-leucine overloading on the level of free amino acids in the diabetic rat].[L-亮氨酸过载对糖尿病大鼠游离氨基酸水平的影响]
C R Seances Soc Biol Fil. 1976;170(1):103-11.
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