Gumínski T
Clin Chim Acta. 1976 Aug 16;71(1):61-6. doi: 10.1016/0009-8981(76)90275-8.
The activities of several glycolytic enzymes (hexokinase, phosphofructokinase, pyruvate kinase, lactate dehydrogenase) as well as glycerol-1-phosphate dehydrogenase and (Mg2+)ATPase in normal cerebrospinal fluid (CSF) and blood plasma samples, from 12 healthy infants, aged 2-18 months, and in supernatants from brain tissue slices, taken during neurosurgical operations from infants of the same range of age were estimated. The values obtained confirm the high activity of the above enzymes found in animal brains, and indicate an independence of these activities in blood plasma and CSF. The origin of the activities of the investigated enzymes in CSF seems to be mainly, if not, exclusively, from brain tissue. This might be useful for detection of brain tissue damage as was earlier proven with LDH activity in CSF.
对12名年龄在2至18个月的健康婴儿的正常脑脊液（CSF）和血浆样本，以及在神经外科手术中取自相同年龄范围婴儿的脑组织切片上清液中的几种糖酵解酶（己糖激酶、磷酸果糖激酶、丙酮酸激酶、乳酸脱氢酶）以及甘油-1-磷酸脱氢酶和（Mg2 +）ATP酶的活性进行了评估。所获得的值证实了在动物脑中发现的上述酶的高活性，并表明这些活性在血浆和脑脊液中具有独立性。脑脊液中所研究酶活性的来源似乎主要（如果不是唯一的话）来自脑组织。这可能有助于检测脑组织损伤，正如先前通过脑脊液中乳酸脱氢酶活性所证明的那样。
