Abu-Musa A, Takahashi K, Nagata H, Yamasaki H, Mizoguchi S, Kitao M
Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan.
Int J Gynaecol Obstet. 1992 Feb;37(2):111-4. doi: 10.1016/0020-7292(92)90491-z.
CA-125 levels in menstrual discharge were determined in 55 patients with chronic pelvic pain to evaluate whether this test would be useful in differentiating between pelvic pain due to endometriosis and other causes. Of the 28 women with endometriosis, 25 (89%) had CA-125 concentration greater than or equal to 72,000 units/ml. The frequencies of elevated levels in Stage I, Stage II and Stages III/IV were 85.7, 85.7 and 92.8%, respectively. When used for the detection of endometriosis, the test had a sensitivity of 89.3% and a specificity of 96.3%. These results suggest that CA-125 in menstrual discharge may be helpful in the evaluation of women with chronic pelvic pain.
对55例慢性盆腔疼痛患者的月经分泌物中的CA - 125水平进行了测定,以评估该检测是否有助于鉴别子宫内膜异位症引起的盆腔疼痛和其他原因引起的盆腔疼痛。在28例患有子宫内膜异位症的女性中,25例(89%)的CA - 125浓度大于或等于72,000单位/毫升。I期、II期和III/IV期CA - 125水平升高的频率分别为85.7%、85.7%和92.8%。当用于检测子宫内膜异位症时,该检测的灵敏度为89.3%,特异性为96.3%。这些结果表明,月经分泌物中的CA - 125可能有助于评估慢性盆腔疼痛的女性。