PAGET G E, SCOTT H M
Br J Pharmacol Chemother. 1957 Dec;12(4):427-33. doi: 10.1111/j.1476-5381.1957.tb00160.x.
A method is described for the assessment of the local reaction produced by intramuscular injections. This method involves the histological examinations of the injection site after injection of material into the hamstring muscles of the rat. The results obtained with both aqueous and oily materials are described; the correlation of these results with clinical observations in man is discussed.
本文描述了一种评估肌肉注射产生的局部反应的方法。该方法包括将材料注射到大鼠的腘绳肌后,对注射部位进行组织学检查。文中描述了水性材料和油性材料的实验结果,并讨论了这些结果与人体临床观察结果的相关性。