Augustsson A, Stierner U, Rosdahl I, Suurküla M
Department of Dermatology, Sahlgren's Hospital, Gothenburg, Sweden.
Acta Derm Venereol. 1992;72(2):123-7.
The role of exposure to ultraviolet light in the formation of melanocytic naevi was analysed by investigating the regional naevus distribution in 310 subjects (30-50 years) from a Swedish census file. The lateral aspect of the arms and the back had the largest concentration of naevi. The mean naevus count per unit surface area was higher in intermittently exposed than in rarely exposed skin (p less than 0.001), while the lowest mean count was found in chronically exposed skin. These results support the idea that intermittent exposure to ultraviolet light has a "naevogenic" effect while chronic exposure might be protective. Dysplastic naevi had a distribution pattern quite different from common naevi. Considering the distribution pattern solely, dysplastic naevi seem to develop independently of exposure to ultraviolet light. The numbers of naevi in different skin areas were tested for their power in predicting the total body naevus count. The strongest correlations were found between total counts and counts on the anterior surface of the thighs and the lateral aspect of the arms. Counts from any of these areas will provide a practical and satisfactory estimate of the total number of naevi.
通过研究来自瑞典人口普查档案的310名年龄在30至50岁之间的受试者的痣分布情况，分析了紫外线暴露在黑素细胞痣形成中的作用。手臂外侧和背部的痣最为密集。间歇性暴露皮肤的每单位表面积平均痣数高于极少暴露的皮肤（p<0.001），而长期暴露皮肤中的平均痣数最低。这些结果支持以下观点：间歇性紫外线暴露具有“致痣”作用，而长期暴露可能具有保护作用。发育异常痣的分布模式与普通痣截然不同。仅从分布模式来看，发育异常痣似乎独立于紫外线暴露而发生。测试了不同皮肤区域的痣数量预测全身痣总数的能力。在总数与大腿前表面和手臂外侧的痣数之间发现了最强的相关性。这些区域中任何一个区域的痣数都将提供对痣总数的实用且令人满意的估计。
