Gasior-Chrzan B, Falk E S
Department of Dermatology, University of Tromsø, Norway.
Acta Derm Venereol. 1992;72(2):138-40.
Significantly lower lysozyme concentrations were found in saliva of 15 psoriatic patients compared with controls, whereas in serum, lysozyme activity, was significantly higher than in controls. The concentrations of IgA in serum of psoriatic patients were significantly higher than in controls, whereas in patients' saliva IgA concentrations were not significantly different from the controls. The findings indicate that lysozyme and IgA may be of significance in the pathophysiology of psoriasis.
与对照组相比，15例银屑病患者唾液中的溶菌酶浓度显著降低，而血清中的溶菌酶活性则显著高于对照组。银屑病患者血清中的IgA浓度显著高于对照组，而患者唾液中的IgA浓度与对照组无显著差异。这些发现表明，溶菌酶和IgA可能在银屑病的病理生理学中具有重要意义。
