Department of Biomedical, Surgical & Dental Sciences, University of Milan, 20122 Milan, Italy.
Department of Women, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Biomed Res Int. 2018 May 20;2018:7290913. doi: 10.1155/2018/7290913. eCollection 2018.
Psoriasis is a skin inflammatory disease characterized by an increased body of comorbidities, including parodontopathy. Despite the visibility of skin lesions, prognostic biomarkers, related to disease monitoring and therapeutic effectiveness, are still missing. Although several markers have been studied, none of them has been identified as an independent prognostic factor. This concise review aims to summarize the current knowledge and results in saliva research applied to psoriasis. Combination of different markers could improve the prognostic prediction in patients with psoriasis. Future studies are needed to implement research on salivary biomarkers and their prognostic/therapeutic effects in the management of patients with psoriasis.
银屑病是一种皮肤炎症性疾病,其特征是合并症增多,包括牙周病。尽管皮肤损伤是可见的,但仍缺乏与疾病监测和治疗效果相关的预后生物标志物。尽管已经研究了几种标志物,但没有一种被确定为独立的预后因素。这篇简明的综述旨在总结目前在银屑病应用唾液研究方面的知识和结果。组合使用不同的标志物可以提高银屑病患者的预后预测。需要进一步的研究来实施对唾液生物标志物及其在银屑病患者管理中的预后/治疗效果的研究。