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Sulfasalazine induced agranulocytosis treated with granulocyte-macrophage colony stimulating factor.

作者信息

Kuipers E J, Vellenga E, de Wolf J T, Hazenberg B P

机构信息

Department of Internal Medicine, University Hospital, Groningen, The Netherlands.

出版信息

J Rheumatol. 1992 Apr;19(4):621-2.

PMID:1350640
Abstract

We report the use of granulocyte-macrophage colony stimulating factor (GM-CSF) in a case of rheumatoid arthritis with sulfasalazine induced agranulocytosis, leading to a rapid bone marrow recovery within 7 days. This case and 2 others reported in the literature emphasize the need for further research into the possible role of GM-CSF in the treatment of drug induced agranulocytosis.

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