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消化性溃疡穿孔疾病的危险因素:一种新评分系统与曼海姆腹膜炎指数的比较

Risk factors in perforated peptic ulcer disease: comparison of a new score system with the Mannheim Peritonitis Index.

作者信息

Altaca G, Sayek I, Onat D, Cakmakçi M, Kamiloğlu S

机构信息

Department of General Surgery, School of Medicine, Hacettepe University, Ankara, Turkey.

出版信息

Eur J Surg. 1992 Apr;158(4):217-21.

PMID:1352135
Abstract

OBJECTIVE

To construct a score that would accurately predict outcome for patients with perforated peptic ulcers.

DESIGN

Retrospective study.

SETTING

University Hospital.

SUBJECTS

173 patients who were operated on for perforated peptic duodenal ulcers over a 14 year period.

MAIN OUTCOME MEASURES

Results of multivariate discriminant function analysis of derived set of clinical variables known to be associated with high mortality, and comparison with the Mannheim Peritonitis Index.

RESULTS

Serious coexisting medical illness, acute renal failure, white cell count of more than 20 x 10(9)/l, and male sex were the most significant factors influencing mortality. The Hacettepe score for perforated peptic ulcer was established using these four variables. The sensitivity was 83%, the specificity 94%, and the overall predictive accuracy 93%. The corresponding figures for the Mannheim Peritonitis Index were 75%, 96%, and 94% respectively.

CONCLUSION

The Hacettepe score is useful in predicting whether a patient will survive after perforation of a peptic duodenal ulcer.

摘要

目的

构建一个能够准确预测消化性溃疡穿孔患者预后的评分系统。

设计

回顾性研究。

地点

大学医院。

研究对象

14年间因十二指肠溃疡穿孔接受手术治疗的173例患者。

主要观察指标

对一组已知与高死亡率相关的临床变量进行多变量判别函数分析的结果,并与曼海姆腹膜炎指数进行比较。

结果

严重并存疾病、急性肾衰竭、白细胞计数超过20×10⁹/L以及男性是影响死亡率的最显著因素。利用这四个变量建立了消化性溃疡穿孔的哈杰泰佩评分系统。其敏感性为83%,特异性为94%,总体预测准确率为93%。曼海姆腹膜炎指数的相应数据分别为75%、96%和94%。

结论

哈杰泰佩评分系统有助于预测十二指肠溃疡穿孔患者能否存活。

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