Nagamine C M, Nishioka Y, Moriwaki K, Boursot P, Bonhomme F, Lau Y F
Vanderbilt University School of Medicine, Department of Cell Biology, Nashville, Tennessee 37232-2175.
Mamm Genome. 1992;3(2):84-91. doi: 10.1007/BF00431251.
Mus musculus domesticus, M.m. bactrianus, M.m. musculus, M.m. castaneus, and M.m. molossinus wild mice were investigated for polymorphisms of the Y Chromosome (Chr) genes Zinc finger-Y (Zfy) and Sex-determining region-Y (Sry). Zfy divided the Y Chrs of these mice into domesticus- (domesticus) and musculus-types (musculus, castaneus, molossinus). M.m. bactrianus specimens had both Y Chrs, possibly owing to the introgression of a musculus-type Y into this population. Sry identified a subpopulation of musculus-type Y chromosomes. This subpopulation, designated the molossinus-type, was found in M.m. molossinus, a M. musculus subspecies specimen from northern China (Changchun), and laboratory mice. The cumulative data suggest that M.m. musculus of northern China and Korea are a subpopulation distinct from M.m. musculus of Europe and central China and that this subpopulation invaded Japan, giving rise to M.m. molossinus. Furthermore, the data suggest that the musculus-type Y of the laboratory mouse originated from this subpopulation, corroborating early historical records reporting that Chinese and Japanese mice that were imported into Europe for the pet trade contributed to the genome of the laboratory mouse.
对小家鼠（Mus musculus domesticus）、双峰小家鼠（M.m. bactrianus）、小家鼠指名亚种（M.m. musculus）、印度小家鼠（M.m. castaneus）和琉球小家鼠（M.m. molossinus）等野生小鼠的Y染色体（Chr）基因锌指-Y（Zfy）和性别决定区-Y（Sry）的多态性进行了研究。Zfy将这些小鼠的Y染色体分为家鼠型（domesticus）和小家鼠型（musculus、castaneus、molossinus）。双峰小家鼠标本同时具有这两种Y染色体，可能是由于小家鼠型Y染色体渗入了这个种群。Sry鉴定出了小家鼠型Y染色体的一个亚群。这个亚群被命名为琉球型，在琉球小家鼠、一只来自中国北方（长春）的小家鼠指名亚种标本以及实验小鼠中被发现。累积的数据表明，中国北方和韩国的小家鼠指名亚种是一个与欧洲和中国中部的小家鼠指名亚种不同的亚群，并且这个亚群侵入了日本，产生了琉球小家鼠。此外，数据表明实验小鼠的小家鼠型Y染色体起源于这个亚群，这证实了早期的历史记录，即因宠物贸易被引入欧洲的中国和日本小鼠对实验小鼠的基因组有贡献。
