Lindström E M, Ohlund L S, Lindström L H, Ohman A
Department of Psychiatry, University of Uppsala, Sweden.
Psychiatry Res. 1992 May;42(2):145-58. doi: 10.1016/0165-1781(92)90078-h.
This study examined whether the response to treatment with neuroleptic medication in 21 schizophrenic patients could be predicted from symptomatology, electrodermal activity, and premorbid adjustment. Positive symptoms and high levels of electrodermal activity were associated with a good response to conventional neuroleptic drugs. However, multivariate analysis indicated that symptomatology was the only independent predictor of treatment response.
本研究探讨了能否根据症状学、皮肤电活动及病前适应情况来预测21例精神分裂症患者使用抗精神病药物治疗的反应。阳性症状及高水平的皮肤电活动与对传统抗精神病药物的良好反应相关。然而,多变量分析表明,症状学是治疗反应的唯一独立预测因素。