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Human mammary epithelial cells in primary culture reflect c-myc and c-erbB-2 gene copy number in tissue.

作者信息

Emerman J T, Wilson S L, Wilkinson D A, Moore D M, Rebbeck P M

出版信息

In Vitro Cell Dev Biol. 1992 Jun;28A(6):377-9. doi: 10.1007/BF02634036.

DOI:10.1007/BF02634036
PMID:1353072
Abstract
摘要

相似文献

1
Human mammary epithelial cells in primary culture reflect c-myc and c-erbB-2 gene copy number in tissue.原代培养的人乳腺上皮细胞反映了组织中的c-myc和c-erbB-2基因拷贝数。
In Vitro Cell Dev Biol. 1992 Jun;28A(6):377-9. doi: 10.1007/BF02634036.
2
Expression of c-myc, c-Ha-ras1, and c-erbB-2 proto-oncogenes in normal and malignant human breast epithelial cells.
J Natl Cancer Inst. 1989 Nov 15;81(22):1704-9. doi: 10.1093/jnci/81.22.1704.
3
Alterations in copy number of c-erbB-2 and c-myc proto-oncogenes in advanced stage of human breast cancer.
Acta Pathol Jpn. 1991 Jan;41(1):19-23. doi: 10.1111/j.1440-1827.1991.tb03267.x.
4
Differential expression of protooncogenes in human germ cell tumors of the testis.原癌基因在人类睾丸生殖细胞肿瘤中的差异表达。
Cancer. 1994 Mar 15;73(6):1721-7. doi: 10.1002/1097-0142(19940315)73:6<1721::aid-cncr2820730628>3.0.co;2-w.
5
Evidence by in situ hybridization that c-erbB-2 proto-oncogene expression is a marker of malignancy and is expressed in lung adenocarcinomas.原位杂交证据表明，c-erbB-2原癌基因表达是恶性肿瘤的一个标志物，且在肺腺癌中表达。
Am J Respir Cell Mol Biol. 1992 Sep;7(3):325-34. doi: 10.1165/ajrcmb/7.3.325.
6
[Oncogenes and anti-oncogenes in breast cancer].[乳腺癌中的癌基因与抗癌基因]
Bull Cancer. 1989;76(7):677-87.
7
Genetic alterations of c-myc, c-erbB-2, and c-Ha-ras protooncogenes and clinical associations in human breast carcinomas.人乳腺癌中c-myc、c-erbB-2和c-Ha-ras原癌基因的遗传改变及临床关联
Cancer Res. 1989 Dec 1;49(23):6675-9.
8
Amplification of c-myc but not of c-erbB-2 is associated with high proliferative capacity in breast cancer.
Cancer Res. 1993 Apr 15;53(8):1956-61.
9
Ras, C-myc and C-erbB-2 oncoprotein expression in non-AIDS Mediterranean Kaposi's sarcoma.非艾滋病相关地中海型卡波西肉瘤中Ras、C-myc和C-erbB-2癌蛋白的表达
Anticancer Res. 1990 Nov-Dec;10(6):1619-25.
10
[Correlation between DNA content and amplification of oncogenes (c-myc, L-myc, c-erbB-2) and correlation with prognosis in 143 cases of resected lung cancer].[143例手术切除肺癌的DNA含量与癌基因（c-myc、L-myc、c-erbB-2）扩增的相关性及其与预后的关系]
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本文引用的文献

1
Amplification of the c-myc oncogene in one of five human breast carcinoma cell lines.五种人乳腺癌细胞系之一中c-myc癌基因的扩增。
Cancer Res. 1984 Feb;44(2):438-41.
2
Changes in gene expression in established human mammary tumor cell lines when compared with normal breast and breast tumor tissue.与正常乳腺组织和乳腺肿瘤组织相比，已建立的人乳腺肿瘤细胞系中的基因表达变化。
Cancer Res. 1986 Nov;46(11):5786-94.
3
Different mitogenic and phenotypic responses of human breast epithelial cells grown in two versus three dimensions.人乳腺上皮细胞在二维和三维培养条件下的不同促有丝分裂和表型反应。
Exp Cell Res. 1986 Dec;167(2):563-9. doi: 10.1016/0014-4827(86)90196-5.
4
Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms.表皮生长因子受体相关原癌基因erbB-2在人乳腺肿瘤细胞系中通过不同分子机制实现过表达。
EMBO J. 1987 Mar;6(3):605-10. doi: 10.1002/j.1460-2075.1987.tb04797.x.
5
Effects of defined medium, fetal bovine serum, and human serum on growth and chemosensitivities of human breast cancer cells in primary culture: inference for in vitro assays.
In Vitro Cell Dev Biol. 1987 Feb;23(2):134-40. doi: 10.1007/BF02623594.
6
Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types.在支持两种细胞类型长期生长的培养基中表达的正常和肿瘤来源的人乳腺上皮细胞的独特特征。
Proc Natl Acad Sci U S A. 1989 Feb;86(4):1249-53. doi: 10.1073/pnas.86.4.1249.
7
Proto-oncogene abnormalities in human breast cancer: c-ERBB-2 amplification does not correlate with recurrence of disease.人类乳腺癌中原癌基因异常：c-ERBB-2基因扩增与疾病复发无关。
Oncogene. 1989 Jan;4(1):105-8.
8
Expression of c-myc, c-Ha-ras1, and c-erbB-2 proto-oncogenes in normal and malignant human breast epithelial cells.
J Natl Cancer Inst. 1989 Nov 15;81(22):1704-9. doi: 10.1093/jnci/81.22.1704.
9
Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: relation to in vivo phenotypes and influence of medium.从正常和恶性组织培养的人乳腺上皮细胞中的角蛋白表达：与体内表型的关系及培养基的影响。
J Cell Sci. 1989 Nov;94 ( Pt 3):403-13. doi: 10.1242/jcs.94.3.403.
10
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer.人类乳腺癌和卵巢癌中HER-2/neu原癌基因的研究。
Science. 1989 May 12;244(4905):707-12. doi: 10.1126/science.2470152.