Künzig M, Steigleder G K
Z Hautkr. 1977 Jan 15;52(2):37-41.
A histologic study was carried out on tissue-reactions after insect bits in 9 patients with various primary diseases. The clinical and cellular reactions to the bite in the epidermis varied, according to the length, intensity of toxity of the insect bit. The dermal infiltrate was similar in almost all cases and corresponded to a cellular immunologic reaction of the early or late type, as is also to be seen in trichophytin and tuberculin-reactions. Tere was clearly no relationship between the character of the dermal infiltrate and the basic disease. We also found no change in the dermal infiltrate due to special medicaments. Even corticosteroids did not suppress the dermal cellular reactions. There was also a striking absence of eosinophil leucocytes in the dermal infiltrate.
对9例患有各种原发性疾病的患者被昆虫叮咬后的组织反应进行了组织学研究。表皮对叮咬的临床和细胞反应因昆虫叮咬的时长、毒性强度而异。几乎在所有病例中，真皮浸润都相似，对应于早期或晚期的细胞免疫反应，这在癣菌素和结核菌素反应中也可见到。真皮浸润的特征与基础疾病之间显然没有关系。我们也未发现特殊药物导致真皮浸润发生变化。即使是皮质类固醇也不能抑制真皮细胞反应。真皮浸润中明显缺乏嗜酸性白细胞。
