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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Maryland Department of Natural Resources, Cooperative Oxford Laboratory, MD 21654.

Comp Biochem Physiol Comp Physiol. 1992 Aug;102(4):727-30. doi: 10.1016/0300-9629(92)90731-5.

Serum proteins from sarcomatous soft shell clams, Mya arenaria L., enhanced transmission of sarcoma. 2. Sarcoma cells were isolated and administered to the recipients at the same cell density in different sarcoma-protein-free diluents: seawater, serum from normal clams, heat-treated sarcoma serum or protease-digested sarcoma serum. 3. Transmission in these groups was significantly slower than in the group where cells were administered in intact sarcoma serum, demonstrating that the tumor promoting factors in the serum were heat-sensitive proteins. 4. Normal hemocytes administered in sarcoma serum caused mortality but not sarcoma transmission, suggesting the presence of cytotoxic factors in sarcoma serum.

来自肉瘤性软壳蛤（Mya arenaria L.）的血清蛋白增强了肉瘤的传播。2. 分离肉瘤细胞，并以相同的细胞密度在不同不含肉瘤蛋白的稀释剂中给予受体：海水、正常蛤的血清、热处理的肉瘤血清或蛋白酶消化的肉瘤血清。3. 这些组中的传播明显慢于在完整肉瘤血清中给予细胞的组，表明血清中的肿瘤促进因子是热敏感蛋白。4. 在肉瘤血清中给予正常血细胞会导致死亡，但不会导致肉瘤传播，提示肉瘤血清中存在细胞毒性因子。

Maryland Department of Natural Resources, Cooperative Oxford Laboratory, MD 21654.

Comp Biochem Physiol Comp Physiol. 1992 Aug;102(4):727-30. doi: 10.1016/0300-9629(92)90731-5.

Serum proteins from sarcomatous soft shell clams, Mya arenaria L., enhanced transmission of sarcoma. 2. Sarcoma cells were isolated and administered to the recipients at the same cell density in different sarcoma-protein-free diluents: seawater, serum from normal clams, heat-treated sarcoma serum or protease-digested sarcoma serum. 3. Transmission in these groups was significantly slower than in the group where cells were administered in intact sarcoma serum, demonstrating that the tumor promoting factors in the serum were heat-sensitive proteins. 4. Normal hemocytes administered in sarcoma serum caused mortality but not sarcoma transmission, suggesting the presence of cytotoxic factors in sarcoma serum.

来自肉瘤性软壳蛤（Mya arenaria L.）的血清蛋白增强了肉瘤的传播。2. 分离肉瘤细胞，并以相同的细胞密度在不同不含肉瘤蛋白的稀释剂中给予受体：海水、正常蛤的血清、热处理的肉瘤血清或蛋白酶消化的肉瘤血清。3. 这些组中的传播明显慢于在完整肉瘤血清中给予细胞的组，表明血清中的肿瘤促进因子是热敏感蛋白。4. 在肉瘤血清中给予正常血细胞会导致死亡，但不会导致肉瘤传播，提示肉瘤血清中存在细胞毒性因子。